Abstract: Clinical Studies of Modified Chimney Method of Uretero-Ileal Anastomosis in the OrthotopicNeobladderWenyuanWU1, Xiaogang LI1, Guojun HOU1, Minhu PIAO1, Shengri TIAN1, Abdul-Ali Yaqubi2, Tiexiong JIN1Correspondence to: Tiexiong JIN, E-mail: jintiexiong0810@hotmail.com1Department of Urology, Affiliated Hospital of Yanbian University, College of Medicine, Yanji 133000, China2Department of Urology, Affiliated Hospital of Balkh Medical College, Balkh Province, AfghanistanAbstrac objective: To investigate the application and efficacy of the modified chimney method of uretero-ileal anastomosis inthe continent W-shape ileal neobladder. Methods: The modified chimney method of uretero-ileal anastomosis was conducted in 62 pa-tients with invasive bladder cancer after radical cystectomy and bladder substitution by continent W-shape ileal neobladder. In 12 pa-tients, the distal end of the ileal loop was first released and brought to the pelvic fossa without detubularization because of the short ilealmesentery. Results: In the current investigation, the average operation time was 300 min and mean blood loss during operation was 988ml. After surgery, the patients were followed up from 12 to 24 months ( average 16 months ). Nineteen patients did not return for followup and eight died. After one year, the average bladder capacity was 500 mL and the residual volume was 0～50 mL. Complications af-ter surgery included 8 cases of hydronephrosis ( 11, 7% ) that resolved after 3 months, 6 cases of transient urine fistula of the neoblad-der ( 9.7% ), 4 cases of acute pyelonephritis ( 6.5% ), and 5 cases of urethral stricture ( 8.1% ). Conclusion: The advantages of the mod-ified chimney method include short surgical duration, fewer complications, less blood loss, and excellent continence.Keywords Urinary diversion; Ileal-neobladder; Chimney modification; Detubularize; Mesentery